Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825380 | 0.86 | NPC1 (0.58) | NPC1RAB9AMAPK1MAPTKMT2A | |
| SCHEMBL825441 | 0.80 | KMT2A (0.50) | MAPTKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL825546 | 0.80 | ELANE (0.54) | NPC1RAB9AMAPK1POLBCYP2C9 | |
| SCHEMBL825497 | 0.80 | MAPT (0.54) | NPC1RAB9ANLRP3MAPK1MAPT | |
| SCHEMBL12892540 | 0.80 | NPC1 (0.57) | NPC1RAB9APOLBKMT2ACYP2C9 | |
| SCHEMBL825379 | 0.79 | ESR1 (0.52) | NPC1RAB9AMAPK1MAPTPOLB | |
| SCHEMBL10294107 | 0.79 | RAB9A (0.71) | NPC1RAB9ANLRP3MAPK1MAPT | |
| SCHEMBL10294799 | 0.79 | KMT2A (0.78) | NPC1RAB9ANLRP3MAPK1MAPT | |
| SCHEMBL23367928 | 0.78 | RAB9A (0.75) | NPC1RAB9ANLRP3MAPK1MAPT | |
| SCHEMBL14572770 | 0.78 | MAPT (0.76) | NPC1RAB9ANLRP3MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8142977-B2 | mixture of resin which decomposes under acid under exposure to actinic radiation, acid generator | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20080241749-A1 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-10-02 | — | — | US | disclosed |