Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698052 | 0.83 | KMT2A (0.41) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL17111461 | 0.76 | L3MBTL1 (0.38) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL6083788 | 0.76 | MEN1 (0.38) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL13306722 | 0.75 | ALOX15 (0.48) | MEN1ALDH1A1TSHRKMT2AMAPK1 | |
| SCHEMBL27832653 | 0.74 | L3MBTL1 (0.37) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL1978409 | 0.72 | — | — | |
| SCHEMBL4277832 | 0.71 | — | — | |
| SCHEMBL19345701 | 0.70 | L3MBTL1 (0.35) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL5689294 | 0.70 | L3MBTL1 (0.37) | L3MBTL1MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL3709979 | 0.70 | L3MBTL1 (0.35) | L3MBTL1MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924593-B9 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO INC (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1924593-B1 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO INC (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2007015787-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007015855-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2006119061-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2006-11-09 | — | — | WO | disclosed |