Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | GPR3 | P46089 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631496 | 0.89 | GPR3 (0.46) | HTR2AGPR3ACHEBCHEHDAC3 | |
| SCHEMBL9017217 | 0.82 | MEN1 (0.36) | HTR2AGPR3ALDH1A1KMT2AMEN1 | |
| Ether SCHEMBL6746857 | 0.81 | HTR2A (0.45) | HTR2AGPR3ACHEBCHEPOLB | |
| SCHEMBL29950614 | 0.76 | GPR3 (0.50) | HTR2AGPR3ACHEBCHEHDAC3 | |
| SCHEMBL524603 | 0.76 | GPR3 (0.50) | HTR2AGPR3ACHEBCHEHDAC3 | |
| Benzene SCHEMBL6809319 | 0.75 | GPR3 (0.44) | HTR2AGPR3ACHEBCHEHDAC3 | |
| SCHEMBL22770492 | 0.74 | HTR2A (0.39) | HTR2AGPR3ALDH1A1CYP2D6KMT2A | |
| SCHEMBL1107108 | 0.73 | GPR3 (0.48) | HTR2AGPR3ACHEBCHEHDAC3 | |
| SCHEMBL21643694 | 0.71 | GPR3 (0.41) | HTR2AGPR3HDAC3HDAC4HDAC7 | |
| Fluoride Ion SCHEMBL3384407 | 0.71 | GPR3 (0.46) | HTR2AGPR3ACHEBCHEHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 363 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572750-B1 | CONTINUOUS PROCESS FOR THE PRODUCTION OF CONTROLLED ARCHITECTURE MATERIALS UNDER HIGH SOLIDS LOADING CONDITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2013-06-19 | — | — | EP | claimed |
| EP-0870780-B1 | Initiator system comprising an heterocyclic ligand for the anionic (co)polymerisation of (meth)acrylic monomers and polymerisation process using it | ATOFINA (FR) | 2004-09-15 | — | — | EP | claimed |
| EP-1304319-A2 | Metallocenes and processes therefor and therewith | Phillips Petroleum Company (US) | 2003-04-23 | — | — | EP | claimed |
| US-6355747-B1 | FOR POLYMERIZATION OF PROPYLENE TO PRODUCE ISOTACTIC POLYPROPYLENE | SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) | 2002-03-12 | — | — | US | claimed |
| US-6262204-B1 | AS POLYMERIZATION INITIATOR FOR POLYMERIZATION OF (METH)ACRYLIC MONOMERS AND OPTIONALLY ETHYLENICALLY UNSATURATED MONOMERS | ATOFINA (FR) | 2001-07-17 | — | — | US | claimed |
| US-20010003726-A1 | INITIATION SYSTEM COMPRISING AN AMINO ALCOHOLATE LIGAND FOR ANIONIC COPOLYMERIZATION OF (METH)ACRYLIC MONOMERS AND PROCESS USING SAME | ELF ATOCHEM S.A. (FR) | 2001-06-14 | — | — | US | claimed |
| EP-1077215-A1 | Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of a-olefins, process for their preparation and use of said metallocenes for the polymerization of a-olefins | SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) | 2001-02-21 | — | — | EP | claimed |
| US-6100416-A | SUCH AS 1-(9-FLUORENYL)-2-(1-(2,4,7-TRIMETHYL)INDENYL)ETHANE ZIRCONIUM DICHLORIDE; SYNTHESIS FROM 1,2-DIBROMOETHANE, FLUORENYLLITHIUM, TRIMETHYLINDENYLLITHIUM, BUTYLLITHIUM AND TRANSITION METAL HALIDE; USE TO MAKE ISOTACTIC POLYPROPYLENE | SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) | 2000-08-08 | — | — | US | claimed |
| US-6069207-A | ANIONIC POLYMERIZATE OF AT LEAST TWO MONOMERS IN PRESENCE OF AT LEAST ONE ALKALI OR ALKALINE EARTH METAL, MONO- OR DIFUNCTIONAL INITIATOR AND LIGAND SELECTED FROM NONNITROGENOUS MACROCYCLIC COMPLEXANT OR ALKALI METAL ALCOHOLATE | ELF ATOCHEM S.A. (FR) | 2000-05-30 | — | — | US | claimed |
| EP-0962462-A2 | Novel asymmetric ethylene-bridged metallocenes useful as catalysts in the polymerization of olefins and process for preparing said metallocenes | SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) | 1999-12-08 | — | — | EP | claimed |
| US-5670592-A | POLYMERIZATION WITH ORGANOLITHIUM COMPOUNDS, PYRIDINE AND ORGANOALUMINUM COMPOUNDS AS CATALYSTS | ELF ATOCHEM S.A. (FR) | 1997-09-23 | — | — | US | claimed |
| EP-0551221-B1 | Process for the preparation of star or network multiblock polycondensates by coupling di- or multi-adhehydes, and polycondensate thus obtained | ATOCHEM ELF SA (FR) | 1997-06-04 | — | — | EP | claimed |
| US-5616752-A | CYCLOPENTADIENYL-TYPE SILANE-CONTAINING POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1997-04-01 | — | — | US | claimed |
| US-5561207-A | USING COORDINATION CATALYST | ELF ATOCHEM S.A. (FR) | 1996-10-01 | — | — | US | claimed |
| EP-0686647-A1 | Process for preparing methyl methacrylate with high level of syndiotactic triads | ELF ATOCHEM S.A. (FR) | 1995-12-13 | — | — | EP | claimed |
| EP-0668297-A1 | Living statistic (meth)acrylat copolymers, copolymers prepared from these living copolymers, and process for preparing these copolymers by anionic copolymerisation | ELF ATOCHEM S.A. (FR) | 1995-08-23 | — | — | EP | claimed |
| US-5399636-A | Bound to inorganic support, olefin polymerization catalysts | PHILLIPS PETROLEUM COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| EP-0628566-A1 | Metallocenes and processes therefor and therewith | PHILLIPS PETROLEUM COMPANY (US) | 1994-12-14 | — | — | EP | claimed |
| US-5346956-A | Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained | ELF ATOCHEM S.A. (FR) | 1994-09-13 | — | — | US | claimed |
| EP-0551221-A1 | Process for the preparation of star or network multiblock polycondensates by coupling di- or multi-adhehydes, and polycondensate thus obtained | ELF ATOCHEM S.A. (FR) | 1993-07-14 | — | — | EP | claimed |