Benzene

Benzene

SCHEMBL6809319

[V]C1c2ccccc2-c2ccccc21.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.44
HTR2A P28223 1/20 0.44
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ATM Q13315 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
CYP1A2 P05177 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.36
ACHE P22303 2/20 0.35
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825558 0.75 HTR2A (0.55) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL524603 0.71 GPR3 (0.50) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL29950614 0.71 GPR3 (0.50) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL1107108 0.69 GPR3 (0.48) GPR3HTR2APOLBMEN1KMT2A
SCHEMBL25171318 0.69 LMNA (0.54) GPR3HTR2ACYP1A2ALDH1A1MAPT
SCHEMBL70993 0.69 LMNA (0.54) GPR3HTR2ACYP1A2ALDH1A1MAPT
SCHEMBL5473773 0.67 HTR2A (0.46) GPR3HTR2APOLBHDAC3HDAC4
SCHEMBL40599 0.67 GPR3 (0.52) GPR3HTR2APOLBMEN1KMT2A
Hydrochloric Acid SCHEMBL3385863 0.67 GPR3 (0.46) GPR3HTR2APOLBMEN1KMT2A
Fluoride Ion SCHEMBL3384407 0.67 GPR3 (0.46) GPR3HTR2APOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0919574-B1 Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared UBE INDUSTRIES (JP) 2004-02-11 EP disclosed
US-6300450-B1 Conjugated diene compound polymerization catalyst process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared UBE INDUSTRIES, LTD. (JP) 2001-10-09 US disclosed
EP-0919574-A1 Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared Ube Industries, Ltd. (JP) 1999-06-02 EP disclosed