SCHEMBL8255679

SCHEMBL8255679

Bc1ccc(Cl)cc1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14014341 0.79
SCHEMBL16363793 0.77 S100A4 (0.42)
SCHEMBL91997 0.75
SCHEMBL31556280 0.75
SCHEMBL406747 0.75
SCHEMBL24351813 0.72 ALDH1A1 (0.48)
SCHEMBL10211770 0.72
SCHEMBL171133 0.72
SCHEMBL167920 0.72
SCHEMBL29719717 0.72 NOTUM (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101522200-A Topical formulations of borinic acid antibodies and their methods of use ANACOR PHARMACEUTICALS INC (US) 2009-09-02 CN claimed
WO-2024050708-A1 BLUE LIGHT EMITTING GUEST MATERIAL AND USE 北京大学深圳研究生院 2024-03-14 WO disclosed
US-20230150254-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-05-18 US disclosed
US-20230131749-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed
CN-110452216-A Anti-fibrosis pyridinone INTERMUNE INC 2019-11-15 CN disclosed
CN-106459042-B Anti-fibrotic pyridinones 英特穆恩公司 2019-06-28 CN disclosed
US-20170358750-A1 HOLE TRANSPORT MATERIALS LG CHEM, LTD. (KR) 2017-12-14 US disclosed
EP-3184590-A1 COLOR DEVELOPING COMPOSITION, LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MAKING LITHOGRAPHIC PRINTING PLATE, AND COLOR DEVELOPER Fujifilm Corporation (JP) 2017-06-28 EP disclosed
CN-106459042-A Anti-fibrotic pyridinones 英特穆恩公司 2017-02-22 CN disclosed
WO-2017019819-A1 FACTOR XIA MACROCYCLIC INHIBITORS BEARING ALKYL OR CYCLOALKYL P2' MOIETIES BRISTOL-MYERS SQUIBB COMPANY (US) 2017-02-02 WO disclosed
EP-2644380-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2016-06-15 EP disclosed
WO-2014201173-A1 BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS AMGEN INC. (US) 2014-12-18 WO disclosed
CN-103037867-A Borinic compositions COLGATE PALMOLIVE CO 2013-04-10 CN disclosed
CN-102781519-A Boronic acid compositions COLGATE PALMOLIVE CO 2012-11-14 CN disclosed
US-20120015966-A1 PPAR ACTIVE COMPOUNDS PLEXXIKON INC 2012-01-19 US disclosed
CN-101522200-A Topical formulations of borinic acid antibodies and their methods of use ANACOR PHARMACEUTICALS INC (US) 2009-09-02 CN disclosed
US-20080221127-A1 peroxisome proliferator-activated receptor agonists; congestive heart failure, atherosclerosis, arteriosclerosis, obesity, hyperlipidemia, hypoalphalipoproteinemia, Syndrome X, diabetes, insulin resistance PLEXXIKON INC 2008-09-11 US disclosed
WO-2006116157-A9 DIPEPTIDYL PEPTIDASE-IV INHIBITORS ALANTOS PHARMACEUTICALS INC (US) 2007-03-01 WO disclosed