Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470628 | 0.87 | FKBP1A (0.54) | FKBP1AACETSHRALDH1A1CYP3A4 | |
| SCHEMBL13928436 | 0.87 | FKBP1A (0.50) | FKBP1AACEPREPTSHRALDH1A1 | |
| SCHEMBL9518270 | 0.80 | PREP (0.68) | FKBP1ASPHK2SPHK1ACEPREP | |
| SCHEMBL1437568 | 0.80 | PREP (0.64) | SPHK2SPHK1PREPTSHRCYP3A4 | |
| SCHEMBL475629 | 0.80 | PREP (0.64) | SPHK2SPHK1PREPTSHRCYP3A4 | |
| SCHEMBL809457 | 0.80 | PREP (0.64) | SPHK2SPHK1PREPTSHRCYP3A4 | |
| SCHEMBL8665486 | 0.80 | ACE (0.53) | FKBP1AACEPREPTSHRALDH1A1 | |
| SCHEMBL14174437 | 0.79 | CMA1 (0.48) | FKBP1AACEPREPTSHRALDH1A1 | |
| SCHEMBL18701774 | 0.77 | FKBP1A (0.65) | FKBP1APREP | |
| SCHEMBL18701786 | 0.77 | FKBP1A (0.65) | FKBP1APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006127702-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2006-11-30 | — | — | WO | disclosed |