Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976980 | 0.88 | ACE (0.57) | ACEITGB3ALDH1A1 | |
| SCHEMBL6976983 | 0.88 | ACE (0.57) | ACEITGB3ALDH1A1 | |
| SCHEMBL8255877 | 0.80 | FKBP1A (0.53) | ACEFKBP1APREPALDH1A1CYP3A4 | |
| SCHEMBL6374284 | 0.78 | LMNA (0.53) | ACEFKBP1AITGB3ALDH1A1 | |
| SCHEMBL3470628 | 0.78 | FKBP1A (0.54) | ACEFKBP1AALDH1A1CYP3A4TSHR | |
| SCHEMBL20484674 | 0.78 | ACE (0.60) | ACEFKBP1APREPALDH1A1CYP3A4 | |
| SCHEMBL18620597 | 0.78 | ACE (0.60) | ACEFKBP1APREPALDH1A1CYP3A4 | |
| SCHEMBL13928436 | 0.77 | FKBP1A (0.50) | ACEFKBP1APREPALDH1A1CYP3A4 | |
| SCHEMBL11764594 | 0.77 | PREP (0.71) | ACEFKBP1APREPALDH1A1 | |
| SCHEMBL2228388 | 0.77 | PREP (0.71) | ACEFKBP1APREPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827860-A | Peptidyl heterocycles useful in the treatment of thrombin related disorders | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-27 | — | — | US | disclosed |