Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128271 | 0.78 | KDM4E (0.36) | SYK | |
| SCHEMBL354239 | 0.78 | CYP2D6 (0.50) | SYK | |
| SCHEMBL29537344 | 0.77 | TSHR (0.37) | HSD17B10KEAP1NFE2L2 | |
| SCHEMBL13559963 | 0.76 | — | — | |
| SCHEMBL16440246 | 0.76 | — | — | |
| SCHEMBL14559401 | 0.76 | — | — | |
| SCHEMBL8225884 | 0.75 | SYK (0.32) | SYK | |
| SCHEMBL8225897 | 0.75 | SYK (0.32) | SYK | |
| SCHEMBL4683204 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL15601970 | 0.72 | GFPT1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130553-A2 | HCV PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |