SCHEMBL8256342

SCHEMBL8256342

Cn1cc(C(=O)Nc2ccc(Cl)cc2)c(C(=O)Nc2ccc(N3CCOC3=N)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.45
F10 P00742 5/20 0.44
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
POLB P06746 2/20 0.41
LMNA P02545 2/20 0.41
MAPKAPK2 P49137 2/20 0.41
NPC1 O15118 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4882290 0.96 F10 (0.43) RAB9AF10MAPTSMN1; SMN2MEN1
SCHEMBL5237942 0.85 F10 (0.36) RAB9AF10MAPTSMN1; SMN2MEN1
SCHEMBL8244509 0.81 F10 (0.52) RAB9AF10MAPTSMN1; SMN2MEN1
SCHEMBL8247423 0.81 LMNA (0.42) RAB9AF10MAPTSMN1; SMN2POLB
SCHEMBL3621342 0.79 F10 (0.51) RAB9AF10MAPTSMN1; SMN2MEN1
SCHEMBL8243190 0.78 F10 (0.48) F10MAPTSMN1; SMN2KMT2APOLB
SCHEMBL3621990 0.78 LMNA (0.40) RAB9AF10MAPTSMN1; SMN2POLB
SCHEMBL13545926 0.78 MAPT (0.53) MAPTSMN1; SMN2MEN1KMT2APOLB
SCHEMBL5231653 0.77 MAPT (0.56) MAPTSMN1; SMN2MEN1KMT2AATM
SCHEMBL4878211 0.77 F10 (0.47) RAB9AF10SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
WO-2006058630-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214533-A1 Cyclic Iminocarbamates And Their Use F2, UQCRB, F12 RAB9A 2655/4885F10 26/4885MAPT 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.