Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CPS1 | P31327 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17438763 | 0.82 | KDM4E (0.49) | HPGDPOLBKMT2AALDH1A1TSHR | |
| SCHEMBL17438783 | 0.81 | KDM4E (0.48) | HPGDPOLBKMT2AALDH1A1TSHR | |
| SCHEMBL16115677 | 0.80 | KDM4E (0.46) | HPGDPOLBKMT2AUSP2ALDH1A1 | |
| SCHEMBL30333846 | 0.79 | POLB (0.45) | POLBPKMMEN1KMT2ACNR2 | |
| SCHEMBL17438482 | 0.79 | KDM4E (0.45) | HPGDPOLBKMT2AUSP2ALDH1A1 | |
| SCHEMBL7456642 | 0.79 | ALDH1A1 (0.56) | HPGDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10272980 | 0.79 | GAA (0.47) | HPGDPOLBLMNAMEN1KMT2A | |
| SCHEMBL29944078 | 0.77 | RBP4 (0.64) | HPGDPOLBMEN1KMT2ATSHR | |
| SCHEMBL2951307 | 0.76 | MEN1 (0.72) | HPGDPOLBLMNAMEN1KMT2A | |
| SCHEMBL29944169 | 0.76 | MEN1 (0.72) | HPGDPOLBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006123257-A2 | PHENYL-3-{(3-(1H-PYRROL-2-YL)-[1, 2 , 4]0XADIAZ0L-5-YL]PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-11-23 | — | — | WO | disclosed |