Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 13/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | HPGD | P15428 | 1/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | CASP1 | P29466 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | CASP7 | P55210 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433473 | 0.90 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29454524 | 0.90 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1914142 | 0.90 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29941043 | 0.89 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL29940884 | 0.89 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8515243 | 0.89 | ADK (0.75) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8206302 | 0.87 | ADK (0.78) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8258002 | 0.86 | ADK (0.71) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8194199 | 0.86 | ADK (1.00) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8214396 | 0.85 | ADK (0.70) | ADKKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |