Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177836 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL294341 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1856208 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL20960041 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL8069055 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL217571 | 0.81 | ALDH1A1 (0.77) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1834864 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL361779 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL25996637 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| Bicarbonate SCHEMBL23001581 | 0.79 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102565-A2 | SYSTEMS AND METHODS FOR NONDESTRUCTIVE TESTING OF GAMETES | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| US-20120295881-A1 | TETRALINE AND INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT GMBH & CO. KG (DE) | 2012-11-22 | — | — | US | disclosed |
| EP-2354851-A2 | Lithographic printing plate precursor and method of preparing lithographic printing plate | Fujifilm Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |
| WO-2011065402-A1 | INDOLE COMPOUND AND PHARMACEUTICAL USE THEREOF | 日本たばこ産業株式会社 (JP) | 2011-06-03 | — | — | WO | disclosed |
| WO-2007012849-A2 | MASS LABELS FOR BIOMOLECULES CONTAINING A 2,6-DIMETHYL-PIPERIDIN-l-YL METHYLENE OR A PYRIMIDIN-2-YL THIOMETHYLENE MASS MARKER MOIETY AND A SUCCINIMID-OXY-CARBONYL REACTIVE FUNCTIONAL GROUP | ELECTROPHORETICS LIMITED (GB) | 2007-02-01 | — | — | WO | disclosed |
| WO-2006106425-A1 | BICYCLIC [3.1.0] HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295881-A1 | TETRALINE AND INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | SLC10A1, SUGT1, SLC10A2 | ALDH1A1 1378/4885MAPK1 1263/4885L3MBTL1 3585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.