Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809271 | 0.90 | HDAC1 (0.71) | HDAC1RAB9ANPC1MAPT | |
| SCHEMBL6509116 | 0.85 | HDAC1 (0.63) | HDAC1 | |
| SCHEMBL1885021 | 0.83 | HDAC1 (0.83) | HDAC1MAPT | |
| SCHEMBL8258701 | 0.81 | HDAC1 (0.75) | HDAC1RAB9ANPC1 | |
| SCHEMBL1893680 | 0.80 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5805563 | 0.78 | HDAC1 (0.73) | HDAC1 | |
| SCHEMBL8260306 | 0.78 | HDAC1 (0.55) | HDAC1RAB9ANPC1MAPT | |
| SCHEMBL1491439 | 0.78 | HDAC1 (0.65) | HDAC1 | |
| SCHEMBL1886609 | 0.77 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5808017 | 0.77 | HDAC1 (0.62) | HDAC1RAB9ANPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |