Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SDCBP | O00560 | 2/20 | 0.42 |
| ▸ | SDC2 | P34741 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7245398 | 0.98 | HPGD (0.49) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11162282 | 0.83 | MAOA (0.66) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1496584 | 0.83 | HPGD (0.47) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11260151 | 0.83 | MAOA (0.66) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29324812 | 0.82 | MAOA (0.44) | HPGDMAOAHTTLMNAMEN1 | |
| SCHEMBL11261318 | 0.79 | SLC6A4 (0.47) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11275306 | 0.79 | SLC6A4 (0.47) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14397430 | 0.79 | SCN4A (0.49) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15855667 | 0.79 | HPGD (0.49) | HPGDMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23393816 | 0.78 | MAOA (0.41) | HPGDMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |