Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255189 | 0.91 | ABHD6 (0.43) | ABHD6DPP8DPP7HPGDDPP4 | |
| SCHEMBL7850122 | 0.90 | ABHD6 (0.42) | ABHD6DPP8HPGDNOTUMACE | |
| SCHEMBL3748218 | 0.85 | PRMT5 (0.47) | ABHD6NOTUMNPC1RAB9APRMT5 | |
| SCHEMBL2612174 | 0.85 | PRMT5 (0.47) | ABHD6NOTUMNPC1RAB9APRMT5 | |
| SCHEMBL8122985 | 0.84 | NAMPT (0.35) | ABHD6DPP8DPP7DPP4DPP9 | |
| Hydrochloric Acid SCHEMBL1635341 | 0.83 | NAMPT (0.35) | ABHD6DPP8DPP7DPP4DPP9 | |
| Hydrochloric Acid SCHEMBL1635343 | 0.83 | NAMPT (0.35) | ABHD6DPP8DPP7DPP4DPP9 | |
| SCHEMBL2102201 | 0.81 | NOTUM (0.45) | ABHD6HPGDNOTUMNPC1RAB9A | |
| SCHEMBL2102200 | 0.81 | NOTUM (0.45) | ABHD6HPGDNOTUMNPC1RAB9A | |
| SCHEMBL8253789 | 0.81 | NOTUM (0.45) | ABHD6HPGDNOTUMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773868-B1 | SUBSTITUTED PROLINES AS INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2006130666-A2 | MEDICAMENTS AND METHODS COMBINING A HCV PROTEASE INHIBITOR AND AN AKR COMPETITOR | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |