Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259154 | 0.91 | ABHD6 (0.41) | ABHD6DPP8HDAC8DPP4DPP7 | |
| SCHEMBL7856938 | 0.89 | ABHD6 (0.43) | ABHD6DPP8HDAC8NOTUMACE | |
| SCHEMBL2100310 | 0.84 | PRMT5 (0.48) | ABHD6NOTUMPRMT5WDR77 | |
| SCHEMBL3739001 | 0.84 | PRMT5 (0.48) | ABHD6NOTUMPRMT5WDR77 | |
| SCHEMBL13223170 | 0.84 | NOTUM (0.52) | ABHD6HDAC8NOTUMHPGDPRMT5 | |
| SCHEMBL13223231 | 0.82 | ELANE (0.44) | PRMT5WDR77 | |
| SCHEMBL2608464 | 0.80 | NOTUM (0.47) | ABHD6NOTUMACEHPGDPRMT5 | |
| SCHEMBL7850122 | 0.80 | ABHD6 (0.42) | ABHD6DPP8NOTUMACEHPGD | |
| SCHEMBL13788468 | 0.79 | BIRC2 (0.36) | ABHD6DPP8DPP4PRMT5WDR77 | |
| SCHEMBL7856943 | 0.79 | CTSL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006130552-A2 | METHODS OF TREATING HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |