Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16979517 | 0.84 | OPRM1 (0.62) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL8261418 | 0.83 | OPRM1 (0.60) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| SCHEMBL10274482 | 0.83 | OPRM1 (0.67) | SLC18A3OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL27821098 | 0.82 | SLC18A3 (0.55) | SLC18A3OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL2440768 | 0.82 | SLC18A3 (0.58) | SLC18A3OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL8437630 | 0.82 | OPRM1 (0.69) | SLC18A3OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL1309812 | 0.82 | SLC18A3 (0.60) | SLC18A3OPRM1KCNH2OPRD1OPRK1 | |
| SCHEMBL16418420 | 0.82 | OPRM1 (0.63) | OPRM1KCNH2GRIN2DGRIN3BCHRM2 | |
| Budipine SCHEMBL4634429 | 0.81 | DRD3 (0.56) | SLC18A3OPRM1KCNH2GRIN2DGRIN3B | |
| SCHEMBL1309331 | 0.80 | TSHR (0.60) | SLC18A3OPRM1KCNH2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER, INC. | 2007-11-29 | — | — | US | disclosed |
| US-7268133-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER, INC. PATENT DEPARTMENT (US) | 2007-09-11 | — | — | US | disclosed |
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | SLC18A3 809/4885OPRM1 6/4885KCNH2 3034/4885 |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | SLC18A3 741/4885OPRM1 7/4885KCNH2 2953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.