Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 4/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.47 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257806 | 0.93 | ACE (0.53) | ACERENPREPPSMB9CALCRL | |
| SCHEMBL13706598 | 0.91 | ACE (0.53) | ACERENELANEPREPPSMB9 | |
| SCHEMBL27809406 | 0.90 | ACE (0.55) | ACERENELANEPREPPSMB9 | |
| SCHEMBL2248710 | 0.88 | ACE (0.53) | ACERENELANEPREPPSMB9 | |
| Carbon Dioxide SCHEMBL2250507 | 0.88 | PREP (0.53) | ACERENELANEPREPPSMB9 | |
| SCHEMBL2248715 | 0.88 | ACE (0.53) | ACERENELANEPREPPSMB9 | |
| SCHEMBL2252313 | 0.85 | REN (0.49) | ACERENELANEPREPPSMB9 | |
| SCHEMBL2252316 | 0.85 | REN (0.49) | ACERENELANEPREPPSMB9 | |
| SCHEMBL2249079 | 0.84 | PREP (0.51) | ACERENELANEPREPPSMB9 | |
| SCHEMBL8257795 | 0.84 | PREP (0.51) | ACERENELANEPREPPSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099261-A2 | POTENT AND SPECIFIC IMMUNOPROTEASOME INHIBITORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-09-21 | — | — | WO | disclosed |