Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.70 |
| ▸ | CTSB | P07858 | 5/20 | 0.70 |
| ▸ | CTSS | P25774 | 3/20 | 0.69 |
| ▸ | TACR1 | P25103 | 2/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234615 | 1.00 | CTSL (0.70) | CTSLCTSBCTSSTACR1CTSK | |
| SCHEMBL4409560 | 1.00 | CTSL (0.70) | CTSLCTSBCTSSTACR1CTSK | |
| SCHEMBL14513407 | 0.95 | CTSL (0.65) | CTSLCTSBCTSSTACR1 | |
| SCHEMBL7028199 | 0.95 | CTSL (0.65) | CTSLCTSBCTSSTACR1 | |
| SCHEMBL7028202 | 0.95 | CTSL (0.65) | CTSLCTSBCTSSTACR1 | |
| SCHEMBL2245863 | 0.90 | CTSL (0.68) | CTSLCTSBCTSS | |
| SCHEMBL7027265 | 0.90 | CTSL (0.75) | CTSLCTSBCTSS | |
| SCHEMBL7027268 | 0.90 | CTSL (0.75) | CTSLCTSBCTSS | |
| SCHEMBL8261584 | 0.90 | CTSL (0.68) | CTSLCTSBCTSS | |
| SCHEMBL7027261 | 0.90 | CTSL (0.75) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589066-B2 | Such as N-carbobenzyloxy-phenylalanyl-phenylalanylal; for treating cancer, inflammation, and/or autoimmune diseases; suppresses endogenous antigenic peptide generation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-09-15 | — | — | US | disclosed |
| US-7589066-B2 | Such as N-carbobenzyloxy-phenylalanyl-phenylalanylal; for treating cancer, inflammation, and/or autoimmune diseases; suppresses endogenous antigenic peptide generation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-09-15 | — | — | US | disclosed |
| WO-2006099261-A2 | POTENT AND SPECIFIC IMMUNOPROTEASOME INHIBITORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-09-21 | — | — | WO | disclosed |