SCHEMBL7028202

SCHEMBL7028202

O=C[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSL P07711 6/20 0.65
CTSB P07858 4/20 0.65
CTSS P25774 2/20 0.64
TACR1 P25103 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7028199 1.00 CTSL (0.65) CTSLCTSBCTSSTACR1
SCHEMBL14513407 1.00 CTSL (0.65) CTSLCTSBCTSSTACR1
SCHEMBL8259359 0.95 CTSL (0.70) CTSLCTSBCTSSTACR1
SCHEMBL23234615 0.95 CTSL (0.70) CTSLCTSBCTSSTACR1
SCHEMBL4409560 0.95 CTSL (0.70) CTSLCTSBCTSSTACR1
SCHEMBL3132335 0.90 CTSB (0.60) CTSLCTSBCTSSTACR1
SCHEMBL7436543 0.90 CTSB (0.60) CTSLCTSBCTSSTACR1
SCHEMBL7028811 0.90 CTSL (0.68) CTSLCTSB
SCHEMBL7028808 0.90 CTSL (0.68) CTSLCTSB
SCHEMBL19015908 0.90 CASP3 (0.60) CTSLCTSBCTSSTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026089565-A1 USE OF CATHEPSIN L INHIBITOR IN COMBINATION ADMINISTRATION 연세대학교 산학협력단 2026-04-30 WO claimed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 US claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 EP claimed
US-20220143128-A1 METHODS FOR TREATING TRAUMATIC BRAIN INJURY BCELL SOLUTIONS, INC. (US) 2022-05-12 US claimed
WO-2022072504-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO, INC. (US) 2022-04-07 WO claimed
EP-3413977-A1 DIPEPTIDYL ALDEHYDES FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES Axiava Pharma UG (DE) 2018-12-19 EP claimed
WO-2017137448-A1 DIPEPTIDYL ALDEHYDES FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AXIAVA PHARMA UG (DE) 2017-08-17 WO claimed
WO-2026059421-A3 NOVEL USE OF CATHEPSIN L INHIBITOR 연세대학교 산학협력단 2026-05-07 WO disclosed
WO-2026089565-A1 USE OF CATHEPSIN L INHIBITOR IN COMBINATION ADMINISTRATION 연세대학교 산학협력단 2026-04-30 WO disclosed
EP-4724502-A1 SINGLE DOMAIN ANTIBODIES DIRECTED AGAINST HUMAN TRANSMEMBRANE- SERINE PROTEASE 2 (TMPRSS2) Institut Pasteur (FR) 2026-04-15 EP disclosed
WO-2026059421-A2 NOVEL USE OF CATHEPSIN L INHIBITOR 연세대학교 산학협력단 2026-03-19 WO disclosed
US-20260053934-A1 DUAL ACTION ONLY PROTEOLYSIS TARGETING CHIMERAS AND USES THEREOF UNIV MASSACHUSETTS (US) 2026-02-26 US disclosed
US-12447142-B2 Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2025-10-21 US disclosed
WO-2022072504-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO, INC. (US) 2022-04-07 WO disclosed
US-20190030113-A1 DIPEPTIDYL ALDEHYDES FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES TRICOLUM PHARMACEUTICALS GMBH (AT) 2019-01-31 US disclosed
EP-3413977-A1 DIPEPTIDYL ALDEHYDES FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES Axiava Pharma UG (DE) 2018-12-19 EP disclosed
WO-2017137448-A1 DIPEPTIDYL ALDEHYDES FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AXIAVA PHARMA UG (DE) 2017-08-17 WO disclosed
WO-2002048097-A9 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS CORVAS INT INC (US) 2003-05-08 WO disclosed
US-20020107266-A1 Compounds, compositions and methods for treatment of parasitic infections DENDREON CORPORATION 2002-08-08 US disclosed
WO-2002048097-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF PARASITIC INFECTIONS CORVAS INTERNATIONAL, INC. (US) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12447142-B2 Compositions and methods for preventing and treating radiation-induced bystander effects caused by radiation or radiotherapy CTSE, CTSB, ATG4B CTSL 26/4885CTSB 2/4885CTSS 4/4885
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS CTSL 13/4885CTSB 2/4885CTSS 3/4885
US-20220143128-A1 METHODS FOR TREATING TRAUMATIC BRAIN INJURY CD74, MIF, MICA CTSL 46/4885CTSB 7/4885CTSS 22/4885
US-20020107266-A1 Compounds, compositions and methods for treatment of parasitic infections CAT, CTSA, CTRL CTSL 26/4885CTSB 6/4885CTSS 5/4885
US-20260053934-A1 DUAL ACTION ONLY PROTEOLYSIS TARGETING CHIMERAS AND USES THEREOF PSMA1, PSMB1, PSME1 CTSL 247/4885CTSB 437/4885CTSS 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.