Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195316 | 0.81 | RXRA (0.47) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL3176733 | 0.79 | RXRA (0.54) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL2312146 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL14286073 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL12743622 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL2095481 | 0.77 | RXRA (0.57) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL1616186 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL694638 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL3546404 | 0.77 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL6147914 | 0.76 | RXRA (0.49) | RXRARXRBRXRGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006056607-A1 | SUBSTITUTED PTERIDINES FOR TREATING INFLAMMATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-01 | — | — | WO | disclosed |