Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24339521 | 0.76 | HTR2A (0.49) | HTR6MEN1KMT2AHTTSLC1A3 | |
| SCHEMBL793097 | 0.76 | CYP2A6 (0.50) | HTR6MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL19465767 | 0.75 | HTR6 (0.36) | HTR6 | |
| SCHEMBL30329138 | 0.75 | ALDH1A1 (0.32) | HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL21515946 | 0.70 | HTT (0.50) | HTR6MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL14896280 | 0.69 | OXER1 (0.40) | HTR6MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL22822842 | 0.68 | CDC7 (0.43) | HTR6KMT2A | |
| SCHEMBL31142624 | 0.68 | HTR6 (0.31) | HTR6ALDH1A1 | |
| SCHEMBL20712499 | 0.67 | HTR6 (0.30) | HTR6 | |
| SCHEMBL16156924 | 0.66 | MAPK11 (0.44) | KMT2AALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006108709-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |