Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672728 | 0.86 | MAPT (0.59) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL5160644 | 0.85 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL5160654 | 0.85 | MAPT (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL5002620 | 0.84 | MAPT (0.50) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL1859542 | 0.84 | MAPT (0.50) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL9656917 | 0.84 | EPHX2 (0.51) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL1068871 | 0.84 | MAPT (0.50) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL17707255 | 0.82 | ALDH1A1 (0.50) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL2692896 | 0.82 | MAPT (0.49) | MAPTCRHBPCRHR2L3MBTL1LMNA | |
| SCHEMBL2692898 | 0.82 | MAPT (0.49) | MAPTCRHBPCRHR2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006115918-A2 | VLA-4 ANTAGONISTS | MERCK & CO., INC. (US) | 2006-11-02 | — | — | WO | disclosed |