Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 10/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259750 | 0.83 | TERT (0.46) | TERTMMEACECPA1ACE2 | |
| SCHEMBL3667413 | 0.83 | TERT (0.46) | TERTMMEACECPA1ACE2 | |
| SCHEMBL25327286 | 0.80 | TERT (0.43) | TERTMMEACECPA1ACE2 | |
| SCHEMBL8533422 | 0.80 | TERT (0.43) | TERTMMEACECPA1ACE2 | |
| SCHEMBL19919650 | 0.80 | TERT (0.43) | TERTMMEACECPA1ACE2 | |
| SCHEMBL7273950 | 0.80 | CYP2D6 (0.45) | TERTMMEACECPA1ACE2 | |
| SCHEMBL8728265 | 0.78 | MME (0.62) | TERTMMEACECPA1ACE2 | |
| SCHEMBL23071542 | 0.78 | TERT (0.43) | TERTMMEACECPA1ACE2 | |
| SCHEMBL10338209 | 0.78 | MME (0.62) | TERTMMEACECPA1ACE2 | |
| SCHEMBL23071543 | 0.78 | TERT (0.43) | TERTMMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006090244-A1 | NEW ADAMANTANE DERIVATIVES AS DIPEPTIDYL, PEPTIDASE IV INHIBITORS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2005075426-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-08-18 | — | — | WO | disclosed |