Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353477 | 0.91 | DPP4 (0.51) | PRCPTHRBALOX12KMT2ADPP4 | |
| SCHEMBL5353470 | 0.91 | DPP4 (0.51) | PRCPTHRBALOX12KMT2ADPP4 | |
| SCHEMBL5281177 | 0.82 | DPP4 (0.49) | PRCPDPP4ALDH1A1FKBP1AACE | |
| SCHEMBL5281181 | 0.82 | DPP4 (0.49) | PRCPDPP4ALDH1A1FKBP1AACE | |
| SCHEMBL5280364 | 0.78 | ALDH1A1 (0.54) | PRCPDPP4ALDH1A1FKBP1A | |
| SCHEMBL5280371 | 0.78 | ALDH1A1 (0.54) | PRCPDPP4ALDH1A1FKBP1A | |
| SCHEMBL5281806 | 0.78 | ITGB1 (0.47) | PRCPDPP4ALDH1A1FKBP1AKDM4E | |
| SCHEMBL5281811 | 0.78 | ITGB1 (0.47) | PRCPDPP4ALDH1A1FKBP1AKDM4E | |
| SCHEMBL5282279 | 0.77 | ITGB3 (0.47) | KMT2ATSHRRAB9A | |
| SCHEMBL5282120 | 0.76 | HDAC1 (0.46) | PRCPDPP4ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |