Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 3/20 | 0.43 |
| ▸ | FLT4 | P35916 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5815917 | 0.85 | NTRK1 (0.65) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL8260616 | 0.82 | KDM4E (0.48) | CYP2C9KDM4EPTGS1PTGS2NTRK1 | |
| SCHEMBL8259565 | 0.82 | KDM4E (0.48) | CYP2C9KDM4EPTGS1PTGS2NTRK1 | |
| SCHEMBL8260918 | 0.81 | KDM4E (0.45) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL5819740 | 0.80 | KDM4E (0.43) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL5819206 | 0.80 | ALDH1A1 (0.49) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL5819647 | 0.79 | KDM4E (0.45) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL5819644 | 0.78 | KDM4E (0.44) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL5804725 | 0.77 | KDM4E (0.44) | KDM4EPTGS1PTGS2NTRK1FLT1 | |
| SCHEMBL8261314 | 0.77 | GAA (0.45) | CYP2C9KDM4EPTGS1PTGS2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |