Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8254604 | 0.95 | TRPV1 (0.46) | TRPV1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL13761492 | 0.86 | RAB9A (0.53) | MAPTALDH1A1KDM4EGAA | |
| SCHEMBL24590133 | 0.84 | MAPT (0.54) | MAPTALDH1A1LMNAKCNQ3KCNQ2 | |
| SCHEMBL15179045 | 0.83 | KDM4E (0.50) | TRPV1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL13006763 | 0.81 | MAPT (0.49) | TRPV1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL8437284 | 0.81 | TRPV1 (0.45) | TRPV1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL4082936 | 0.80 | KCNQ3 (0.48) | TRPV1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL11833547 | 0.76 | RAB9A (0.53) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL4082931 | 0.76 | KCNQ3 (0.48) | TRPV1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL26739746 | 0.76 | MAPT (0.45) | TRPV1MAPTALDH1A1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER, INC. | 2007-11-29 | — | — | US | disclosed |
| US-7268133-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER, INC. PATENT DEPARTMENT (US) | 2007-09-11 | — | — | US | disclosed |
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | TRPV1 16/4885MAPT 2827/4885ALDH1A1 1683/4885 |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | TRPV1 20/4885MAPT 3003/4885ALDH1A1 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.