Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310233 | 0.86 | TAAR1 (0.66) | ADORA3ADORA2AADORA1ALDH1A1POLB | |
| SCHEMBL18456226 | 0.85 | MME (0.63) | ADORA3ADORA2AADORA1HSD17B10ALDH1A1 | |
| SCHEMBL4151615 | 0.85 | MME (0.63) | ADORA3ADORA2AADORA1HSD17B10ALDH1A1 | |
| SCHEMBL12205972 | 0.85 | MME (0.63) | ADORA3ADORA2AADORA1HSD17B10ALDH1A1 | |
| SCHEMBL26456643 | 0.84 | MGLL (0.54) | MGLLHSD17B10TSHRHDAC1HDAC6 | |
| SCHEMBL12805649 | 0.84 | MGLL (0.66) | MGLLADORA1ALDH1A1POLBCNR1 | |
| SCHEMBL23951499 | 0.82 | MGLL (0.55) | MGLLADORA3HSD17B10TSHRHDAC1 | |
| SCHEMBL13515716 | 0.82 | ALDH1A1 (0.68) | HSD17B10TSHRALDH1A1POLB | |
| SCHEMBL2742152 | 0.81 | ALDH1A1 (0.57) | HSD17B10TSHRALDH1A1 | |
| SCHEMBL1750966 | 0.81 | TAAR1 (0.73) | MGLLADORA3HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |