Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201299 | 0.94 | NPC1 (0.47) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201440 | 0.82 | RAB9A (0.43) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201114 | 0.80 | RAB9A (0.48) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1202361 | 0.80 | RAB9A (0.47) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201596 | 0.79 | RAB9A (0.46) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201851 | 0.79 | RAB9A (0.52) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201542 | 0.76 | HPGDS (0.47) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1202185 | 0.76 | RAB9A (0.43) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1202055 | 0.75 | RAB9A (0.50) | RAB9ANPC1PKMHSP90AA1PAX8 | |
| SCHEMBL1201719 | 0.75 | NPC1 (0.40) | RAB9ANPC1PKMHSP90AA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099379-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2006-09-21 | — | — | WO | disclosed |