Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886031 | 0.86 | BPTF (0.45) | HTR2AHTR2CHTR2BBPTFSLC6A4 | |
| SCHEMBL3886029 | 0.86 | BPTF (0.45) | HTR2AHTR2CHTR2BBPTFSLC6A4 | |
| SCHEMBL3887869 | 0.86 | BPTF (0.45) | HTR2AHTR2CHTR2BBPTFSLC6A4 | |
| SCHEMBL3886033 | 0.86 | BPTF (0.45) | HTR2AHTR2CHTR2BBPTFSLC6A4 | |
| SCHEMBL3886540 | 0.72 | ADRA2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL1897659 | 0.71 | HTR2C (0.59) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL9278829 | 0.71 | HTR2C (0.59) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9672275 | 0.69 | HTR2C (0.57) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL3019601 | 0.69 | BPTF (0.48) | HTR2AHTR2CHTR2BBPTFCHRNB2 | |
| SCHEMBL12635734 | 0.68 | PNMT (0.43) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006097293-A2 | COMBINATION OF A STEROID SULFATASE INHIBITOR AND AN ASCOMYCIN | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |