Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117920 | 1.00 | GID4 (0.37) | GID4POLBHSD17B10GAACYP19A1 | |
| SCHEMBL10459608 | 0.74 | GID4 (0.32) | GID4CYP19A1TBXAS1MEN1KMT2A | |
| SCHEMBL14530666 | 0.70 | HTR1A (0.30) | — | |
| SCHEMBL13117925 | 0.70 | HTR1A (0.30) | — | |
| SCHEMBL6101683 | 0.70 | GID4 (0.37) | GID4POLBHSD17B10CYP19A1TBXAS1 | |
| SCHEMBL16363077 | 0.69 | CYP19A1 (0.42) | GID4POLBHSD17B10GAACYP19A1 | |
| SCHEMBL13845052 | 0.69 | CYP19A1 (0.42) | GID4CYP19A1TBXAS1 | |
| SCHEMBL7508090 | 0.69 | CYP19A1 (0.42) | GID4POLBHSD17B10GAACYP19A1 | |
| SCHEMBL12900509 | 0.69 | CYP19A1 (0.42) | GID4CYP19A1TBXAS1 | |
| SCHEMBL16363090 | 0.69 | CYP19A1 (0.42) | GID4POLBHSD17B10GAACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851193-B1 | HIV PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007048557-A1 | PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-05-03 | — | — | WO | disclosed |
| WO-2006084688-A1 | HIV protease inhibitors | MEDIVIR AB (SE) | 2006-08-17 | — | — | WO | disclosed |