SCHEMBL826317

SCHEMBL826317

[NH]C(=O)c1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120212 0.80
SCHEMBL937615 0.80
SCHEMBL1066873 0.79 CES2 (1.00)
SCHEMBL182010 0.79 CES2 (0.71)
Hydrochloric Acid SCHEMBL485645 0.78
Urea SCHEMBL4239865 0.78 CES2 (0.62)
Hydrochloric Acid SCHEMBL3194035 0.78 CES2 (0.62)
Thiophene Carboxylic Acid SCHEMBL83000 0.77
Thiophene Carboxylic Acid SCHEMBL7062244 0.77 DAO (1.00)
SCHEMBL225933 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436975-B 2-trifluoromethyl-4-aminoquinazoline compound and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-10-31 CN claimed
CN-107033157-B Bisbenzylisoquinoline derivative and application thereof in preparing medicament for treating or preventing tumor 贵州省中国科学院天然产物化学重点实验室 2020-05-05 CN claimed
US-20190183889-A1 PLASMODIAL SURFACE ANION CHANNEL INHIBITORS FOR THE TREATMENT OR PREVENTION OF MALARIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) 2019-06-20 US claimed
US-10265313-B2 Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2019-04-23 US claimed
US-10189812-B2 Bi-benzyl isoquinoline derivative, preparation method and use thereof in hepatopathy treatment and prevention THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUC (CN) 2019-01-29 US claimed
US-20180015086-A1 PLASMODIAL SURFACE ANION CHANNEL INHIBITORS FOR THE TREATMENT OR PREVENTION OF MALARIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) 2018-01-18 US claimed
US-20170260161-A1 BI-BENZYL ISOQUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF IN HEPATOPATHY TREATMENT AND PREVENTION VERSITECH LIMITED (CN) 2017-09-14 US claimed
US-9573887-B2 Naphthalene derivative DAITO CHEMIX CORPORATION (JP) 2017-02-21 US claimed
US-20160193207-A1 PLASMODIAL SURFACE ANION CHANNEL INHIBITORS FOR THE TREATMENT OR PREVENTION OF MALARIA THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2016-07-07 US claimed
US-9198426-B2 Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-01 US claimed
US-4931438-A Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-05 US claimed
EP-0346511-A1 Oxygen-containing hererocyclic compound, processes for their preparation and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-12-20 EP claimed
US-4870075-A AGRICULTURE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-26 US claimed
US-4684731-A NEUROLEPTIC, ANTIEMETIC, ANALGESIC HOFFMANN-LA ROCHE INC. (US) 1987-08-04 US claimed
US-4643849-A ANTIULCER, ANTISECRETORY AGENTS TOYAMA CHEMICAL CO., LTD. (JP) 1987-02-17 US claimed
EP-0037990-B1 PHENYL QUINOLIZIDINES, CORRESPONDING PHARMACEUTICAL PREPARATIONS, THE PREPARATION OF THE ACTIVE COMPOUNDS AND CORRESPONDING STARTING COMPOUNDS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-12-05 EP claimed
EP-0037990-A1 Phenyl quinolizidines, corresponding pharmaceutical preparations, the preparation of the active compounds and corresponding starting compounds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-10-21 EP claimed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US claimed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US claimed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US claimed