Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.71 |
| ▸ | CES1 | P23141 | 2/20 | 0.71 |
| ▸ | HPGDS | O60760 | 1/20 | 0.71 |
| ▸ | DAO | P14920 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL8081415 | 0.93 | HPGDS (0.63) | CES2CES1HPGDSDAOHPGD | |
| SCHEMBL6494787 | 0.91 | HPGD (0.72) | CES2CES1HPGDSDAOHPGD | |
| SCHEMBL6793430 | 0.87 | HPGDS (0.83) | CES2CES1HPGDSDAOHPGD | |
| SCHEMBL9148337 | 0.85 | LMNA (0.85) | CES2CES1HPGDSDAOHPGD | |
| SCHEMBL158020 | 0.84 | HPGDS (1.00) | CES2CES1HPGDSDAOHPGD | |
| SCHEMBL1066873 | 0.83 | CES2 (1.00) | CES2CES1HPGDSDAOHPGD | |
| Propionaldehyde SCHEMBL7337468 | 0.83 | HPGDS (0.53) | CES2CES1HPGDSDAOHPGD | |
| Water SCHEMBL28007578 | 0.82 | HPGDS (0.96) | CES2CES1HPGDSDAOHPGD | |
| Thiophene Carboxylic Acid SCHEMBL83000 | 0.81 | — | — | |
| SCHEMBL225933 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 811 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624278-B2 | Downhole methods and compositions used in such | DORF KETAL CHEMICALS FZE (AE) | 2026-05-12 | — | — | US | claimed |
| US-12577453-B2 | Downhole methods and compositions used in such | DORF KETAL CHEMICALS FZE (AE) | 2026-03-17 | — | — | US | claimed |
| US-12497557-B2 | Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore | DORF KETAL CHEMICALS FZE (AE) | 2025-12-16 | — | — | US | claimed |
| CN-119392254-A | Acid etching solution for display panel multilayer film, preparation method and application thereof | 浙江奥首材料科技有限公司 | 2025-02-07 | — | — | CN | claimed |
| US-20250011644-A1 | NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH | DORF KETAL CHEMICALS FZE (AE) | 2025-01-09 | — | — | US | claimed |
| CN-119019315-A | 10, 10-Dimethyl anthrone derivative and organic electroluminescent device thereof | 西安欧得光电材料有限公司 | 2024-11-26 | — | — | CN | claimed |
| US-20240279533-A1 | DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH | DORF KETAL CHEMICALS FZE (AE) | 2024-08-22 | — | — | US | claimed |
| US-20240254383-A1 | NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH | DORF KETAL CHEMICALS FZE (AE) | 2024-08-01 | — | — | US | claimed |
| US-20240191128-A1 | Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore | DORF KETAL CHEMICALS FZE (AE) | 2024-06-13 | — | — | US | claimed |
| CN-114057684-B | Synthesis method of tiotropium bromide intermediate methyl bis (2-dithienyl) glycolate | 鲁南制药集团股份有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-101781310-A | Thiofuran-pyridine [3, 2-c] contained acethydrazide derivative and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2010-07-21 | — | — | CN | claimed |
| CN-101166722-A | Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles | WYETH CORP (US) | 2008-04-23 | — | — | CN | claimed |
| CN-1968987-A | Monomer, oligomer and pi-conjugated polymer compounds, and photovoltaic cells containing same | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2007-05-23 | — | — | CN | claimed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | claimed |
| US-20010056085-A1 | Methods of using vesicant drug formulations | RAMU AVNER (US) | 2001-12-27 | — | — | US | claimed |
| US-6117223-A | Hot melt inks containing polyketones | XEROX CORPORATION (US) | 2000-09-12 | — | — | US | claimed |
| US-5591381-A | REACTION OF KETONE AND ALDEHYDE WITH ACID IN THE PRESENCE OF ANTIMONY OR BISMUTH COMPOUNDS | HALLIBURTON COMPANY (US) | 1997-01-07 | — | — | US | claimed |
| US-5354836-A | Polyarylene ether ketone, where at least one ring of the aromatic ketone unit is a thiophene ring | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1994-10-11 | — | — | US | claimed |
| EP-0291853-B1 | THIENON COMPOUNDS | BASF Aktiengesellschaft (DE) | 1993-07-28 | — | — | EP | claimed |
| US-4908437-A | Thien-2-one compounds with an alkylidene or imino group in the 5-position of the ring | BASF AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056085-A1 | Methods of using vesicant drug formulations | UGT1A1, SLC47A1, UGT1A10 | CES2 221/4885CES1 1758/4885HPGDS 422/4885 |
| US-12577453-B2 | Downhole methods and compositions used in such | IL1B, IL17A, GET3 | CES2 4538/4885CES1 3630/4885HPGDS 964/4885 |
| US-12624278-B2 | Downhole methods and compositions used in such | IL17A, IL1B, GET3 | CES2 4637/4885CES1 3840/4885HPGDS 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.