Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | ATF4 | P18848 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262387 | 0.90 | ADRB3 (0.39) | LMNABCHEACHEHTTADRB3 | |
| SCHEMBL4896440 | 0.89 | ADRB3 (0.43) | ATF4LMNAALDH1A1HTTADRB3 | |
| SCHEMBL4896452 | 0.89 | ADRB3 (0.43) | ATF4LMNAALDH1A1HTTADRB3 | |
| SCHEMBL4897702 | 0.80 | ADRB3 (0.53) | LMNAADRB3 | |
| SCHEMBL4897688 | 0.80 | ADRB3 (0.53) | LMNAADRB3 | |
| SCHEMBL8263805 | 0.80 | ADRB3 (0.53) | LMNAADRB3 | |
| SCHEMBL4902951 | 0.78 | ADRB2 (0.41) | LMNANPY1RNPY2RADRB3MAPT | |
| SCHEMBL4902961 | 0.78 | ADRB2 (0.41) | LMNANPY1RNPY2RADRB3MAPT | |
| SCHEMBL4903507 | 0.77 | ATF4 (0.43) | ATF4LMNAALDH1A1HTTADRB3 | |
| SCHEMBL4902501 | 0.77 | ADRB2 (0.44) | LMNANPY1RNPY2RADRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060122-A9 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS INC (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006060122-A2 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |