⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789686 | 0.86 | EPHX2 (0.46) | — | |
| SCHEMBL9946326 | 0.83 | DPP4 (0.47) | — | |
| SCHEMBL10611575 | 0.82 | DPP4 (0.47) | — | |
| SCHEMBL6052795 | 0.78 | — | — | |
| SCHEMBL4160072 | 0.78 | — | — | |
| SCHEMBL5069160 | 0.78 | — | — | |
| SCHEMBL9944489 | 0.78 | DPP4 (0.43) | — | |
| SCHEMBL24102652 | 0.77 | L3MBTL1 (0.58) | — | |
| SCHEMBL15158364 | 0.77 | BLM (0.44) | — | |
| Hydrochloric Acid SCHEMBL8552428 | 0.77 | DPP7 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162522-A1 | HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-28 | — | — | WO | disclosed |
| US-8044198-B2 | Sirtuin modulating compounds | SIRTRIS PHARMACEUTICALS, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| WO-2011037793-A1 | SUBSTITUTED AMINOPIPERIDINES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2011-03-31 | — | — | WO | disclosed |
| US-20090099170-A1 | Sirtuin modulating compounds | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2007057128-A1 | NOVEL DUAL PEPTIDASE INHIBITORS AS PRODRUGS FOR THE THERAPY OF INFLAMMATORY AND OTHER DISORDERS | IMTM GMBH (DE) | 2007-05-24 | — | — | WO | disclosed |
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |