⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557070 | 0.86 | ALDH1A1 (0.52) | — | |
| SCHEMBL10611575 | 0.82 | DPP4 (0.47) | — | |
| SCHEMBL23145226 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL4160072 | 0.78 | — | — | |
| SCHEMBL6052795 | 0.78 | — | — | |
| SCHEMBL8264016 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8552428 | 0.77 | DPP7 (0.51) | — | |
| Hydrochloric Acid SCHEMBL6162602 | 0.77 | DPP7 (0.51) | — | |
| SCHEMBL4419351 | 0.77 | DPP4 (0.48) | — | |
| SCHEMBL9494472 | 0.77 | DPP4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256420-B | Tetrahydropyridopyrimidine derivatives, their preparation and use | 江西中医药大学 | 2020-04-28 | — | — | CN | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-7230002-B2 | Dipeptidyl peptidase IV inhibitors; processes for their preparation and compositions thereof | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-4775676-A | ANTIINFLAMMATORY AGENTS | CHIESI FARMACEUTICI S.P.A. (IT) | 1988-10-04 | — | — | US | disclosed |