Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8251009 | 0.88 | FFAR1 (0.65) | PPARGPPARAFFAR1MAPTLMNA | |
| SCHEMBL8264168 | 0.86 | PPARG (0.50) | PPARGPPARAFFAR1GAAFFAR4 | |
| SCHEMBL8264139 | 0.84 | KDM4E (0.59) | PPARGPPARAMAPTGAANPC1 | |
| SCHEMBL8265550 | 0.84 | SMN1; SMN2 (0.54) | PPARGPPARAFFAR1MAPTLMNA | |
| SCHEMBL7733929 | 0.83 | MAPT (0.66) | PPARGMAPTLMNAGAANPC1 | |
| SCHEMBL13376460 | 0.82 | PPARG (0.47) | PPARGPPARAFFAR1MAPTLMNA | |
| SCHEMBL8976610 | 0.82 | KMT2A (0.62) | MAPTLMNAMAOBGAAMAPK1 | |
| SCHEMBL8266366 | 0.81 | SMN1; SMN2 (0.74) | MAPTLMNAGAAMAPK1NPC1 | |
| SCHEMBL18563422 | 0.80 | MAPT (0.49) | MAPTLMNAFFAR4NPC1RAB9A | |
| SCHEMBL8264152 | 0.79 | FFAR4 (0.50) | PPARGPPARAFFAR1GAAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |