Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8264191 | 0.90 | RAB9A (0.59) | SMN1; SMN2RAB9ANPC1HPGDMAPK1 | |
| SCHEMBL8265550 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1MAPK1LMNA | |
| SCHEMBL13458590 | 0.84 | KMT2A (0.67) | SMN1; SMN2RAB9ANPC1HPGDMAPK1 | |
| SCHEMBL8251009 | 0.81 | FFAR1 (0.65) | SMN1; SMN2RAB9ANPC1MAPK1LMNA | |
| SCHEMBL8264165 | 0.81 | PPARG (0.51) | SMN1; SMN2RAB9ANPC1MAPK1LMNA | |
| SCHEMBL19002729 | 0.81 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1HPGDMAPK1 | |
| SCHEMBL8264139 | 0.81 | KDM4E (0.59) | RAB9ANPC1HPGDMAPTGAA | |
| SCHEMBL8264168 | 0.80 | PPARG (0.50) | SMN1; SMN2MAPK1GAAPOLB | |
| SCHEMBL12171985 | 0.77 | HIF1A (0.85) | SMN1; SMN2RAB9ANPC1MAPK1LMNA | |
| SCHEMBL13376460 | 0.77 | PPARG (0.47) | SMN1; SMN2RAB9ANPC1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |