Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.61 |
| ▸ | RARB | P10826 | 8/20 | 0.54 |
| ▸ | RARG | P13631 | 8/20 | 0.54 |
| ▸ | RARA | P10276 | 5/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747196 | 0.84 | RARB (0.53) | RARBRARGRARAHNF4ACYP26A1 | |
| SCHEMBL18125275 | 0.83 | VCP (0.51) | FFAR1RARBRARGRARAHNF4A | |
| Hydrochloric Acid SCHEMBL6923419 | 0.82 | RARB (0.51) | RARBRARGRARAHNF4ACYP26A1 | |
| SCHEMBL8264835 | 0.82 | FFAR1 (0.57) | FFAR1FFAR4GRM5ALDH1A1CA12 | |
| SCHEMBL8154161 | 0.81 | ACACB (0.56) | FFAR1RARBRARGRARAHNF4A | |
| SCHEMBL20022591 | 0.81 | ALDH1A1 (0.74) | FFAR1RARBRARGRARACYP26A1 | |
| Terephthalic Acid SCHEMBL8103061 | 0.81 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL402518 | 0.81 | RARB (0.62) | FFAR1RARBRARGRARAFFAR4 | |
| SCHEMBL4946180 | 0.81 | GRM5 (0.62) | FFAR1FFAR4HNF4ACYP3A4GRM5 | |
| SCHEMBL10809316 | 0.81 | FFAR1 (0.60) | FFAR1RARBRARGRARAHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |