SCHEMBL8264189

SCHEMBL8264189

Cc1cccc(-c2ccc(OCCN)cc2)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
LTA4H P09960 2/20 0.47
PLA2G2A P14555 1/20 0.47
FFAR4 Q5NUL3 1/20 0.46
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
DRD3 P35462 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
MAOB P27338 2/20 0.43
FFAR1 O14842 1/20 0.43
LSS P48449 1/20 0.42
ICMT O60725 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8265107 0.85 CYP3A4 (0.47) LTA4HFFAR4DRD2DRD4DRD3
SCHEMBL8264152 0.85 FFAR4 (0.50) FFAR4DRD2DRD4DRD3PPARG
SCHEMBL2623677 0.81 NQO1 (0.52) LTA4HSMN1; SMN2PPARGPPARAFFAR1
SCHEMBL8264173 0.81 LSS (0.59) LTA4HMAOBLSS
SCHEMBL7408051 0.80 TAAR1 (0.57) TAAR1LTA4HPLA2G2ADRD2DRD4
SCHEMBL30230126 0.80 TAAR1 (0.57) TAAR1LTA4HPLA2G2ADRD2DRD4
SCHEMBL9488010 0.80 LTA4H (0.66) TAAR1LTA4HPLA2G2AFFAR4DRD2
SCHEMBL4904165 0.80 TAAR1 (0.75) TAAR1LTA4HPLA2G2ASMN1; SMN2LSS
SCHEMBL29237868 0.80 TAAR1 (0.65) TAAR1LTA4HPLA2G2ASMN1; SMN2LSS
SCHEMBL8264198 0.80 LSS (0.71) FFAR4DRD2DRD3SMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006069788-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2006-07-06 WO disclosed