Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356443 | 0.78 | PDE4D (0.62) | PDE4DACHE | |
| SCHEMBL31356442 | 0.78 | PDE4D (0.62) | PDE4DACHE | |
| SCHEMBL13094739 | 0.75 | MAOA (0.47) | — | |
| SCHEMBL11744257 | 0.73 | ESR2 (0.54) | PDE4D | |
| SCHEMBL23856225 | 0.73 | NOTUM (0.53) | — | |
| SCHEMBL30063573 | 0.73 | NOTUM (0.53) | — | |
| SCHEMBL587912 | 0.71 | ESR2 (0.31) | — | |
| SCHEMBL23856210 | 0.71 | HRH3 (0.41) | MAP3K5 | |
| SCHEMBL23856219 | 0.71 | KEAP1 (0.50) | — | |
| SCHEMBL30062709 | 0.71 | HRH3 (0.41) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065215-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |