Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098550 | 0.91 | ALDH1A1 (0.55) | MAOBALDH1A1ABCB1APPENPP2 | |
| SCHEMBL8263658 | 0.91 | PTPN1 (0.51) | MAOBTACR1ALDH1A1GRM5ENPP2 | |
| SCHEMBL13618144 | 0.87 | CALM1 (0.51) | MAOBTACR1 | |
| SCHEMBL14664397 | 0.87 | PARP10 (0.51) | MAOBTACR1GRM5 | |
| SCHEMBL31644032 | 0.85 | MAOB (0.69) | MAOBTACR1GRM5ABCB1APP | |
| SCHEMBL14456120 | 0.85 | PARP10 (0.53) | MAOBTACR1GRM5 | |
| SCHEMBL13498482 | 0.85 | PARP10 (0.53) | MAOBGRM5 | |
| SCHEMBL5987976 | 0.83 | MAOB (0.76) | MAOBABCB1APP | |
| SCHEMBL12903697 | 0.83 | MAOB (0.47) | MAOBALDH1A1ABCB1APPENPP2 | |
| SCHEMBL14456118 | 0.82 | PARP10 (0.55) | MAOBTACR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |