Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239516 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTOPRK1DRD2 | |
| SCHEMBL3235882 | 0.89 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTOPRM1OPRD1 | |
| SCHEMBL8265566 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTOPRD1OPRK1 | |
| SCHEMBL3241301 | 0.81 | MEN1 (0.42) | ALDH1A1KDM4EMAPTHPGDMTTP | |
| SCHEMBL3244243 | 0.81 | MEN1 (0.49) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL3238315 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDMTTP | |
| SCHEMBL3235817 | 0.79 | TAS1R3 (0.41) | ALDH1A1KDM4EMAPTHPGDMTTP | |
| SCHEMBL3238418 | 0.78 | MEN1 (0.45) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL3239591 | 0.78 | KMT2A (0.47) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL3233194 | 0.77 | CNR1 (0.40) | ALDH1A1KDM4EMAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067423-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |