Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300649 | 0.86 | CYP1A2 (0.42) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL11503562 | 0.85 | CNR1 (0.48) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL89112 | 0.85 | AHR (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL17534018 | 0.84 | CNR1 (0.42) | PTGS2CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL17534016 | 0.84 | CYP1A2 (0.42) | PTGS2CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL8264024 | 0.82 | EGFR (0.41) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL11504030 | 0.82 | NR5A1 (0.53) | CNR1CNR2 | |
| SCHEMBL13131319 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL662039 | 0.80 | FDPS (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL3919902 | 0.80 | CNR1 (0.40) | ALDH1A1SMN1; SMN2BACE1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |