Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905138 | 0.86 | ATM (0.44) | ATMALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL3233013 | 0.81 | SLC6A9 (0.42) | ATMALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL3244606 | 0.80 | TAS1R3 (0.44) | ATMALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL3238820 | 0.78 | SLC6A9 (0.41) | ATMALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL3238177 | 0.76 | TAS1R3 (0.41) | ATMALDH1A1HPGDTAS1R3TAS1R1 | |
| SCHEMBL8265269 | 0.76 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL8265761 | 0.76 | ITGB1 (0.42) | ALDH1A1HPGDTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3907148 | 0.75 | SLC6A9 (0.47) | ALDH1A1SLC6A9L3MBTL1LMNA | |
| SCHEMBL3239591 | 0.73 | KMT2A (0.47) | ALDH1A1HPGDSLC6A9CA12CA1 | |
| SCHEMBL3902029 | 0.73 | ITGB1 (0.43) | ALDH1A1HPGDSLC6A9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067417-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |