SCHEMBL8265707

SCHEMBL8265707

ClC1=C(Cl)CCC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4063689 0.81 ALDH1A1 (0.37)
SCHEMBL4063697 0.81 ALDH1A1 (0.37)
SCHEMBL2511413 0.79 ALDH1A1 (0.36)
SCHEMBL3453406 0.79 ALDH1A1 (0.36)
SCHEMBL2898862 0.79 ALDH1A1 (0.36)
SCHEMBL3778455 0.79 ALDH1A1 (0.36)
SCHEMBL3453404 0.79 ALDH1A1 (0.36)
SCHEMBL2511411 0.79 ALDH1A1 (0.36)
SCHEMBL30418037 0.79 ALDH1A1 (0.36)
SCHEMBL3003651 0.74 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166156-B Tyrosine kinase inhibitors, compositions and methods 贝达药业股份有限公司 2024-02-27 CN claimed
CN-114634491-B Polycyclic compound for inhibiting RNA helicase DHX33 成都开悦生命科技有限公司 2024-03-19 CN disclosed
CN-113166156-B Tyrosine kinase inhibitors, compositions and methods 贝达药业股份有限公司 2024-02-27 CN disclosed
CN-110291095-B Adenosine analogues and their use in regulating circadian clock 北京生命科学研究所 2023-04-18 CN disclosed
CN-114634491-A Polycyclic compound for inhibiting RNA helicase DHX33 成都开悦生命科技有限公司 2022-06-17 CN disclosed
CN-106458923-B Heterocyclic compound 株式会社大熊制药 2019-09-10 CN disclosed
US-20190261891-A1 BREATH ANALYSIS DEVICE INVOY HOLDINGS INC. 2019-08-29 US disclosed
US-10226201-B2 Flow regulation device for breath analysis and related method INVOY HOLDINGS, LLC (US) 2019-03-12 US disclosed
US-20170224251-A1 BREATH ANALYSIS SYSTEM CAPABLE OF CONTROLLING FLOW OF AN EXHALED BREATH SAMPLE INTO AN INSERTABLE CARTRIDGE INVOY HOLDINGS, LLC 2017-08-10 US disclosed
US-20170119279-A1 FLOW REGULATION DEVICE FOR BREATH ANALYSIS AND RELATED METHOD INVOY HOLDINGS INC. 2017-05-04 US disclosed
US-20170119280-A1 FLOW REGULATION DEVICE FOR BREATH ANALYSIS AND RELATED METHOD INVOY HOLDINGS, LLC 2017-05-04 US disclosed
CN-106458923-A Novel heterocyclic compound 株式会社大熊制药 2017-02-22 CN disclosed
EP-2411009-B1 Therapeutic uses of quinazolinedione derivatives SANOFI SA (FR) 2013-03-20 EP disclosed
WO-2012142067-A2 FORMULATIONS, SALTS, AND SOLID FORMS OF SUBSTITUTED CYCLOHEXYLMETHANAMINES, PROCESSES FOR PREPARATION, AND USES THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2012-10-18 WO disclosed
WO-2006056930-A2 NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS ACTELION PHARMACEUTICALS LTD (CH) 2006-06-01 WO disclosed
US-5466763-A High performance epoxy resin modified by a polysulfide polymer derived from the heavy ends waste of chlorinated hydrocarbon production FORMOSA PLASTICS CORPORATION (US) 1995-11-14 US disclosed
US-5432257-A Process for manufacturing a polysulfide polymer from the heavy ends waste of chlorinated hydrocarbon production FORMOSA PLASTICS CORPORATION (US) 1995-07-11 US disclosed
US-4025495-A POLLUTION CONTROL TESSENDERLO CHEMIE S.A. (BE) 1977-05-24 US disclosed
US-4005156-A Novel flame retardant compositions of matter UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-01-25 US disclosed