Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266946 | 0.80 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5097161 | 0.77 | F10 (0.79) | F10F2KLK1PRSS1PRSS2 | |
| SCHEMBL8266910 | 0.72 | GFER (0.45) | F10 | |
| SCHEMBL5100150 | 0.71 | F10 (0.79) | F10F2KLK1PRSS1PRSS2 | |
| SCHEMBL8165396 | 0.71 | F10 (1.00) | F10KCNH2F2PRSS1PRSS2 | |
| SCHEMBL8169824 | 0.71 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8408044 | 0.70 | F10 (0.72) | F10KCNH2F2 | |
| SCHEMBL14176283 | 0.70 | F10 (0.80) | F10F2KLK1PRSS1PRSS2 | |
| SCHEMBL8166604 | 0.70 | F10 (0.92) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8162813 | 0.70 | F10 (1.00) | F10KCNH2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006047528-A2 | PYRAZOLOBENZAMIDES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-04 | — | — | WO | disclosed |