Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.74 |
| ▸ | F2 | P00734 | 5/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100150 | 0.90 | F10 (0.79) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8165396 | 0.85 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169824 | 0.85 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5097161 | 0.84 | F10 (0.79) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14176283 | 0.83 | F10 (0.80) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8169081 | 0.83 | F10 (0.84) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14176284 | 0.81 | F10 (0.74) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8163056 | 0.81 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8266608 | 0.80 | F10 (0.58) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8165136 | 0.79 | F10 (0.85) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006047528-A2 | PYRAZOLOBENZAMIDES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-04 | — | — | WO | disclosed |