Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 13/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266497 | 0.84 | SLC6A9 (0.44) | SLC6A9GPR139CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3239482 | 0.83 | SLC6A9 (0.62) | SLC6A9 | |
| SCHEMBL13303748 | 0.76 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL5014899 | 0.75 | SLC6A9 (0.59) | SLC6A9 | |
| SCHEMBL3238634 | 0.74 | SLC6A9 (0.59) | SLC6A9 | |
| SCHEMBL3239804 | 0.71 | SLC6A9 (0.47) | SLC6A9 | |
| SCHEMBL631883 | 0.71 | SLC6A9 (0.64) | SLC6A9GPR139CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3244891 | 0.70 | SLC6A9 (0.59) | SLC6A9GPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3245146 | 0.70 | SLC6A9 (0.58) | SLC6A9 | |
| SCHEMBL3230692 | 0.70 | SLC6A9 (0.48) | SLC6A9TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067423-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |