Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17551619 | 0.89 | SMN1; SMN2 (0.33) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13475733 | 0.87 | ALDH1A1 (0.33) | ALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7509910 | 0.86 | ALDH1A1 (0.36) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8266825 | 0.85 | ALDH1A1 (0.35) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7527377 | 0.82 | OPRM1 (0.32) | ALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL17568763 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7515928 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL14617472 | 0.82 | ALDH1A1 (0.32) | ALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL7534109 | 0.81 | ALDH1A1 (0.34) | ALDH1A1GAAL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7531228 | 0.81 | OPRL1 (0.38) | ALDH1A1GAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065277-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |